Table 1 Characteristics of the treatment groups
Radiosurgery alone N patients (%) | Radiosurgery + WBRT N patients (%) | P -value | |
|---|---|---|---|
Radiosurgery dose | |||
<20 Gy (n = 23) | 10 (33) | 13 (46) | |
≥20 Gy (n = 35) | 20 (67) | 15 (54) | 0.63 |
Age | |||
≤59 years (n = 34) | 17 (57) | 17 (61) | |
≥60 years (n = 24) | 13 (43) | 11 (39) | 0.94 |
ECOG performance score | |||
0-1 (n = 40) | 20 (67) | 20 (71) | |
2 (n = 18) | 10 (33) | 8 (29) | 0.93 |
Number of cerebral metastases | |||
1 (n = 46) | 25 (83) | 21 (75) | |
2-3 (n = 12) | 5 (17) | 7 (25) | 0.84 |
Maximum diameter of all brain metastases | |||
≤10 mm (n = 28) | 15 (50) | 13 (46) | |
≥11 mm (n = 30) | 15 (50) | 15 (54) | 0.95 |
Site of brain metastases | |||
Supratentorial (n = 39) | 20 (67) | 19 (68) | |
Infratentorial ± supratentorial (n = 19) | 10 (33) | 9 (32) | 0.98 |
Extra-cranial metastases | |||
No (n = 24) | 11 (37) | 13 (46) | |
Yes (n = 34) | 19 (63) | 15 (54) | 0.75 |
Time from breast cancer diagnosis to radiotherapy | |||
≤48 months (n = 30) | 15 (50) | 15 (54) | |
≥49 months (n = 28) | 15 (50) | 13 (46) | 0.95 |