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Table 4 Treatment responses according to treatment modality and type of plasma cell-proliferative disorder

From: The role of radiotherapy in the management of POEMS syndrome

Feature No. of Pts, Clinical response Hematologic response
No. of patients (%) No. of patients (%)
Improved Mixed Stable Progression CR H VGPR H PR H NR H
RT 4 3 (75) 0 (0) 1 (25) 0 (0) 1 (25) 1 (25) 0 (0) 2 (50)
CHT 16 11 (69) 1 (6) 2 (13) 2 (13) 5 (31) 2 (13) 4 (25) 5 (31)
RT + CHT 9 8 (89) 0 (0) 0 (0) 1 (11) 4 (44) 1 (11) 1 (11) 3 (33)
Steroid or Ig 4 1 (25) 1 (25) 1 (25) 1 (25) 0 (0) 0 (0) 0 (0) 4 (100)
OSM 13 11 (84) 0 (0) 1 (8) 1 (8) 6 (46) 1 (8) 3 (23) 3 (23)
CD 4 2 (50) 0 (0) 1 (25) 1 (25) 0 (0) 1 (25) 2 (50) 1 (25)
OSM + CD 10 7 (70) 1 (10) 1 (10) 1 (10) 3 (30) 2 (20) 0 (0) 5 (50)
VEGFe 6 3 (50) 1 (17) 1 (17) 1 (17) 1 (17) 0 (0) 0 (0) 5 (83)
  1. Pts, patients; CR, complete response; VGPR, very good partial response; PR, partial response; NR, no response; RT, radiotherapy; CHT, chemotherapy; Ig, immunoglobulin; OSM, osteosclerotic myeloma; CD, Castleman’s disease; VEGFe, vascular endothelial growth factor elevation without growth lesion.