Skip to main content

Table 2 POEMS features of the study patients

From: The role of radiotherapy in the management of POEMS syndrome

Characteristic All (n = 33) RT ( n = 13) Non-RT ( n = 20) p value *
No. of patients (%) No. of patients (%) No. of patients (%)
Polyneuropathy     
 Peripheral neuropathy 33 (100) 13 (100) 20 (100) N/A
 CSF protein >50 mg/dL 18/20 (90) 5/5 (100) 13/15 (87) 1.00
Organomegaly     
 Hepatomegaly 16 (48) 6 (46) 10 (50) 1.000
 Splenomegaly 18 (55) 7 (54) 11 (55) 0.614
 Lymphadenopathy 15 (45) 5 (38) 10 (50) 0.722
Endocrinopathy     
 Diabetes mellitus 6 (18) 3 (23) 3 (15) 0.659
 Hypothyroidism 15 (45) 3 (23) 12 (60) 0.072
 Gonadal axis abnormality 10 (30) 3 (23) 7 (35) 0.701
 Adrenal axis abnormality 8 (24) 5 (38) 3 (15) 0.213
 Hyperparathyroidism 0 (0) 0 (0) 0 (0) N/A
Skin changes     
 Hyper-pigmentation 25 (76) 11 (85) 14 (70) 0.431
 Acrocyanosis and plethora 1 (3) 0 (0) 1 (5) 1.000
 Hemangioma/telangiectasia 0 (0) 0 (0) 0 (0) N/A
 Hypertrichosis 16 (48) 6 (46) 10 (50) 1.000
Extravascular volume overload     
 Peripheral edema 19 (58) 6 (46) 13 (65) 0.472
 Ascites 12 (36) 1 (8) 11 (55) 0.009
 Pleural effusion 13 (39) 1 (8) 12 (60) 0.004
 Pericardial effusion 7 (21) 0 (0) 7 (35) 0.027
Types of bone lesion     
 Osteolytic 4 (12) 2 (15) 2 (10) 0.488
 Osteosclerotic 14 (42) 7 (54) 7 (35)
 Mixed 5 (15) 4 (31) 1 (5)
No. of bone lesion     
 None 10 (30) 0 (0) 10 (50) 0.008
 Solitary 11 (33) 7 (54) 4 (20)  
 Multiple 12 (36) 6 (46) 6 (30)
  1. RT, radiotherapy; CSF, cerebrospinal fluid; N/A, not applicable.
  2. *The p value was calculated by the Pearson’s Chi-squared test between RT and non-RT.