Table 2 Organs at risk

Cord

PRIM

0.1 cc

Dmax ≤ 44-45 Gy

Dmax 46 Gy

Cord (PRV)

PRIM

0.1 cc

Dmax 44–48 Gy

Dmax 48–50 Gy

Brain

PRIM

1 cc

Dmax 60 Gy

Dmax 63 Gy

Temporal lobes

PRIM

1 cc

Dmax 60 Gy

Dmax 65 Gy

Brainstem (PRV)

PRIM

0.1 cc

Dmax 54 Gy

Dmax 60 Gy

Chiasm (PRV)

PRIM

0.1 cc

Dmax 54 Gy

Dmax 60 Gy

Optic nerve (PRV)

PRIM

0.1 cc

Dmax 54 Gy

Dmax 60 Gy

Larynx

PRIM

1 cc

Dmax 73.5 Gy

Dmax 77 Gy

Mandible

PRIM

1 cc

Dmax 70–73.5 Gy

Dmax 75–77 Gy

Inner ear

SEC

D mean

<50 Gy

<52.5 Gy

Larynx (without cartilaginous framework)

SEC

V50

<25%

<30%

Oedema

Larynx (supraglottis)

SEC

Dmax

<66 Gy

Dysphonia

Larynx (whole organ)

SEC

Dmax

<50 Gy

Aspiration

Mandible

SEC

V55

<20%

Esophagus

SEC

1 cc

Dmax 45 Gy

Dmax 55 Gy

Parotid gland

SEC

V30

<50%

<60%

at least one

SEC

Dmean

≤26 Gy

at least one

SEC

V40

<33% (contralat)

Upper GI mucosa (outside PTV)

SEC

1 cc

<30 Gy

<36 Gy

Upper GI mucosa (whole volume)

SEC

V66.5

Dmax 64 Gy (<3 %?)

Dmax 70 Gy (<5%)

Brachial plexus

PRIM

0.1 cc

Dmax 60 Gy

Dmax 66 Gy

SEC in selected

Thyroid Gland

SEC

V45

<50%

Submandibular gl

SEC

Dmean

<35 Gy

Constrictor pharyngeal mm

SEC

Dmean

<50 Gy

Lacrimal gland

PRIM

Dmean

26 Gy

SEC in selected cases

Lens

PRIM

Dmax

<4 Gy

<6 Gy

SEC in selected cases

Retina

PRIM

0.1 cc

Dmax 54 Gy

Dmax 60 Gy

Pituitary gland

SEC

Dmax

<50 Gy

TM joints

PRIM

0.1 cc

<70Gy