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Table 4 Predictors of grade 2+ xerostomia at 6 months by univariate and multivariate logistic regression

From: Submandibular gland-sparing radiation therapy for locally advanced oropharyngeal squamous cell carcinoma: patterns of failure and xerostomia outcomes

  Univariate Multivariate
Variable Odds ratio (95% CI) P value Odds ratio (95% CI) P value
Contralateral SMG dose (Gy) 1.07 (1.05-1.11) <0.0001 1.07 (1.02-1.11) 0.002
Contralateral parotid dose (Gy) 1.10 (1.02-1.21) 0.03 0.92 (0.81-1.04) 0.19
T4 tumor 5.63 (2.21-15.31) 0.0004 3.90 (1.10-14.95) 0.04
Bilateral nodal disease 6.07 (2.26-17.85) 0.0005 2.67 (0.62-12.01) 0.19
Base of tongue primary 1.94 (0.84-4.55) 0.12 2.30 (0.71-7.95) 0.17
Concurrent systemic therapy 5.88 (1.01-111.52) 0.10 2.51 (0.33-53.76) 0.44
Age at treatment 1.03 (0.98-1.08) 0.31 1.02 (0.96-1.09) 0.56