Table 3 Measures of quality, monitor units, treatment times and scattered dose for the four plan scenarios (median values ± standard deviation (minimum-maximum), and p-values of pair-wise tests)
From: mARC vs. IMRT radiotherapy of the prostate with flat and flattening-filter-free beam energies
Index | 6 MV IMRT | 7 MV IMRT | 6 MV mARC | 7 MV mARC | p (6 MV IMRT – mARC) | p (7 MV IMRT – mARC) | p (IMRT 6 MV – 7 MV) | p (mARC 6 MV – 7 MV) |
|---|---|---|---|---|---|---|---|---|
CI | 0.896 ± 0.024 (0.855-0.945) | 0.883 ± 0.014 (0.864-0.910) | 0.909 ± 0.017 (0.878-0.925) | 0.883 ± 0.024 (0.850-0.926) | n.s. | n.s. | 0.029 | 0.004 |
HI | 0.096 ± 0.010 (0.080-0.111) | 0.100 ± 0.010 (0.093-0.122) | 0.091 ± 0.011 (0.085-0.121) | 0.102 ± 0.010 (0.088-0.126) | n.s. | n.s. | 0.010 | 0.027 |
Bladder V50Gy (%) | 21.0 ± 14.0 (6.3-48.7) | 22.1 ± 14.1 (6.3-48.2) | 20.8 ± 14.2 (6.0-49.3) | 22.4 ± 14.6 (6.7-49.8) | n.s. | n.s. | n.s. | 0.004 |
Rectum V50Gy (%) | 16.9 ± 5.1 (5.9-22.2) | 17.2 ± 5.2 (7.1-23.7) | 16.8 ± 5.2 (5.3-22.3) | 17.5 ± 5.5 (5.7-23.4) | n.s. | n.s. | n.s. | 0.049 |
Post. Rect. Wall V40Gy (%) | 3.8 ± 3.4 (0.0-9.7) | 3.6 ± 4.2 (0.0-12.7) | 3.5 ± 3.2 (0.0-8.3) | 4.8 ± 4.2 (0.0-11.6) | n.s. | n.s. | n.s. | 0.043 |
MU | 402 ± 29 (365–442) | 402 ± 25 (368–445) | 414 ± 29 (365–452) | 411 ± 43 (366–507) | 0.047 | n.s. | n.s. | n.s. |
Treatment time (min:sec) | 5:21 ± 0:10 (5:09–5:40) | 4:31 ± 0:04 (4:25–4:39) | 3:35 ± 0:12 (3:20–3:55) | 2:27 ± 0:09 (2:13–2:39) | 0.002 | 0.002 | 0.002 | 0.002 |
Dose at navel (mGy) | 15.5 ± 2.1 (12.8-18.8) | 12.2 ± 1.7 (10.8-15.3) | 14.6 ± 2.3 (12.7-19.0) | 12.4 ± 2.2 (10.3-16.7) | n.s. | n.s. | 0.002 | 0.002 |
Dose at manubrium (mGy) | 1.47 ± 0.2 (1.21-1.86) | 1.25 ± 0.2 (1.06-1.59) | 1.52 ± 0.2 (1.33-1.87) | 1.29 ± 0.2 (0.97-1.58) | n.s. | n.s. | 0.002 | 0.002 |
Dose at lens (mGy) | 0.597 ± 0.046 (0.534-0.689) | 0.351 ± 0.030 (0.320-0.423) | 0.597 ± 0.050 (0.563-0.705) | 0.378 ± 0.037 (0.322-0.449) | n.s. | 0.020 | 0.002 | 0.002 |