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Table 1 Effect of motion on tumor target dose distribution in fifteen patients

From: Dynamic simulation of motion effects in IMAT lung SBRT

Constraints Difference between 3D planned dose and cumulative 4D doses Mean (min, max) 4D inter-fraction variation Mean (min, max) Difference between cumulative 4D doses with and without motion Mean (min, max)
PTV V90% −0.48% (−1.44%, 0.25%) 0.20% (0.00%,1.89%) −0.35% (−1.22%, 0.83%)
PTV V95% −0.10% (−1.22%, 1.31%) 0.12% (0.00%, 1.38%) −0.26% (−1.06%, 1.97%)
PTV V105% −5.04% (−13.88%, 9.71%) 1.66% (0.00%, 6.87%) 2.75% (−5.90%, 4.65%)
V_Presp. Iso./V_PTV −0.15 (−0.31, −0.01) 0.04 (0.00,0.15) −0.30 (−0.91, −0.01)
V_50% Pres. Iso./V_PTV −0.14 (−0.68, 0.06) 0.05 (0.00, 0.24) −0.32 (−1.63, 0.00)
D2cm −0.22 Gy (−2.20 Gy, 1.70 Gy) 0.45 Gy (0 Gy, 1.20 Gy) −1.14 Gy (−4.00 Gy, 0.10 Gy)
  1. The mean values are cumulative dose differences averaged over all patients. The mean values of the 4D inter-fraction variation are the average of the largest variations among four fractions over all patients.