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Table 1 Effect of motion on tumor target dose distribution in fifteen patients

From: Dynamic simulation of motion effects in IMAT lung SBRT

Constraints

Difference between 3D planned dose and cumulative 4D doses Mean (min, max)

4D inter-fraction variation Mean (min, max)

Difference between cumulative 4D doses with and without motion Mean (min, max)

PTV V90%

−0.48% (−1.44%, 0.25%)

0.20% (0.00%,1.89%)

−0.35% (−1.22%, 0.83%)

PTV V95%

−0.10% (−1.22%, 1.31%)

0.12% (0.00%, 1.38%)

−0.26% (−1.06%, 1.97%)

PTV V105%

−5.04% (−13.88%, 9.71%)

1.66% (0.00%, 6.87%)

2.75% (−5.90%, 4.65%)

V_Presp. Iso./V_PTV

−0.15 (−0.31, −0.01)

0.04 (0.00,0.15)

−0.30 (−0.91, −0.01)

V_50% Pres. Iso./V_PTV

−0.14 (−0.68, 0.06)

0.05 (0.00, 0.24)

−0.32 (−1.63, 0.00)

D2cm

−0.22 Gy (−2.20 Gy, 1.70 Gy)

0.45 Gy (0 Gy, 1.20 Gy)

−1.14 Gy (−4.00 Gy, 0.10 Gy)

  1. The mean values are cumulative dose differences averaged over all patients. The mean values of the 4D inter-fraction variation are the average of the largest variations among four fractions over all patients.