Table 1 Patient characteristics and results of short- and long-term survivors with glioblastoma
Patient characteristics of STS and LTS | ||
|---|---|---|
STS; n = 50 | LTS; n = 5O | |
Age (years) | 64, 8 | 51, 9 |
< 60 years | 16 (32) | 35 (60) |
> 60 years | 34 (68) | 15 (30) |
< 70 years | 34 (68) | 43 (86) |
> 70 years | 16 (32) | 7 (14) |
Male | 33 (66) | 26 (52) |
Female | 17 (34) | 24 (48) |
Tumor location | ||
Right hemisphere | 16 (32) | 24 (48) |
Left hemisphere | 24 (48) | 23 (46) |
Both hemispheres | 10 (20) | 3 (6) |
Location close to the ventricle (< 10 mm) | 44 (88) | 33 (68, 8) |
Location distant to the ventricle (≥ 10 mm) | 6 (12) | 15 (31, 3) |
Involvement of the ventricle system | 30 (60) | 18 (39, 1) |
Multifocal disease | 12 (24) | 7 (15, 2) |
Subependymal spread | 15 (30) | 5 (10, 9) |
Extent of resection | ||
Biopsy | 26 (52) | 5 (10, 4) |
Total resection | 7 (14) | 22 (45,8) |
Partial resection | 17 (34) | 22 (45,8) |
Ventricle opening during surgery | 8 (16) | 17 (34,7) |
Classification (Lim et al.) | ||
Type I | 18 (36) | 21 (43,8) |
Type II | 16 (32) | 6 (12, 5) |
Type llI | 9 (18) | 15 (31, 3) |
Type IV | 7 (14) | 6 (125) |
MGMT hypermethyation | 4 (36, 4) | 12 (70, 6) |
Radiotherapy within a study | 23 (46) | 25 (50) |
GD (Gy) | 56, 8 | 45, 1 |
RT as Re-irradiation | 3 (6) | 15 (30) |
Radiochemotherapy | 35 (70) | 38 (76) |
Temozolomide | 32 (64) | 35 (70) |