From: Evaluation of volumetric modulated arc therapy for postmastectomy treatment
Structure/Item | Metric | VMAT | HT | p-value |
---|---|---|---|---|
PTV | DV95% (Gy) | 49.3 ± 0.1 | 49.8 ± 0.1 | <0.001 |
DHI | 0.147 ± 0.009 | 0.096 ± 0.005 | <0.001 | |
CI | 0.778 ± 0.008 | 0.719 ± 0.008 | <0.001 | |
TCP | 99.8 ± 0.2 | 100 ± 0.0 | 0.002 | |
Total lung | V5Gy (%) | 66.2 ± 3.1 | 89.8 ± 1.4 | <0.001 |
V20Gy (%) | 16.3 ± 0.2 | 15.0 ± 0.3 | <0.001 | |
NTCP (%) | 0.3 ± 0.1 | 0.6 ± 0.1 | 0.06 | |
SCCP (%) | 5.3 ± 0.1 | 6.1 ± 0.0** | <0.001 | |
Ipsilateral lung | V5Gy (%) | 96.9 ± 1.3 | 99.3 ± 0.5 | 0.06 |
V20Gy (%) | 32.3 ± 0.8 | 29.9 ± 1.0 | <0.001 | |
Contralateral lung | V5Gy (%) | 37.8 ± 4.9 | 81.7 ± 2.5 | <0.001 |
Heart* | V15Gy (%) | 26.0 ± 1.9 | 28.2 ± 2.6 | 0.4 |
Dmean (Gy) | 12.9 ± 0.5 | 14.4 ± 0.6 | 0.04 | |
Dmax (Gy) | 42.2 ± 1.6 | 38.3 ± 1.3 | <0.001 | |
NTCP (%) | 1.3 ± 0.2 | 0.9 ± 0.1 | 0.008 | |
Contralateral breast | Mean dose (Gy) | 1.5 ± 0.1 | 1.8 ± 0.1 | <0.001 |
SCCP (%) | 1.0 ± 0.0** | 1.2 ± 0.0** | <0.001 | |
Non-specific normal tissue | Mean dose (Gy) | 7.0 ± 0.2 | 11.1 ± 0.4 | <0.001 |
SCCP (%) | 0.7 ± 0.0 | 0.9 ± 0.0** | <0.001 | |
Efficiency | Delivery time (s) | 128.6 ± 2.8 | 382.4 ± 10.9 | <0.001 |