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Table 2 Univariate and multivariate analyses of grade +2 GI and GU toxicity

From: Improvement in toxicity in high risk prostate cancer patients treated with image-guided intensity-modulated radiotherapy compared to 3D conformal radiotherapy without daily image guidance

GI Toxicity Univariate analysis Multivariate analysis
Parameter Hz 95% CI p-value Hz 95% CI p-value
Age 0.93 0.89-0.97 <0.001* 0.99 0.93-1.04 0.584
Performance status 1.67 0.73-3.85 0.227 1.84 0.70-4.82 0.218
Comorbidity 1.18 0.75-1.86 0.482 0.88 0.62-1.77 0.878
Smoking 1.05 0.62-1.77 0.853 0.71 0.51-1.58 0.708
3DCRT vs IG-IMRT 12.81 7.84-20.92 <0.001* 11.59 6.67-20.14 <0.001*
Adjuvant ADT 0.31 0.16-0.60 0.001* 0.27 0.13-0.56 <0.001*
GU toxicity Univariate analysis Multivariate analysis
Parameter Hz 95% CI p-value Hz 95% CI p-value
Age 1.00 0.97-1.04 0.869 1.01 0.97-1.05 0.476
Performance status 1.80 0.99-3.24 0.052 1.68 0.89-3.18 0.111
Comorbidity 1.50 1.07-2.11 0.018* 1.50 1.02-2.21 0.038*
Smoking 1.27 0.89-1.81 0.185 1.28 0.88-1.88 0.200
3DCRT vs IG-IMRT 1.58 1.10-2.26 0.013* 1.72 1.11-2.67 0.015*
Adjuvant ADT 0.60 0.34-1.06 0.078 0.57 0.30-1.06 0.075
  1. *Statistically significant.