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Table 5 Comparison of PSA kinetics between CK and CF-EBRT by Gleason score and age subsets: probability values

From: Hypofractionated SBRT versus conventionally fractionated EBRT for prostate cancer: comparison of PSA slope and nadir

  

Gleason score 3 + 3

Gleason score 3 + 4

 

Through year:

  

Nadir PSA (ng/mL)

   
 

1

ns

ns

  

p = 0.01

p = 0.03

  

p = 0.03

p = 0.02

Time to Nadir PSA (mos.)

   
 

1

ns

ns

 

2

ns

ns

 

3

p = 0.02

ns

Rate of PSA change: ng/mL/month

   
 

1

ns

ns

 

2

p = 0.02

ns

 

3

p = 0.01

ns

  

Age < 70

Age ≥ 70

Nadir PSA (ng/mL)

   
 

1

ns

ns

 

2

p = 0.002

p = 0.03

 

3

p = 0.01

ns

Time to Nadir PSA (mos.)

   
 

1

ns

ns

 

2

ns

ns

 

3

p = 0.004

ns

Rate of PSA change: ng/mL/Month

   
 

1

ns

ns

 

2

ns

ns

 

3

(p = 0.09)

p = 0.03

  1. For each Gleason score subset (3 + 3 vs 3 + 4) and age subset (<70 vs ≥70) the PSA outcomes were compared between SBRT and CF-EBRT. The distributions for PSA nadir and PSA slope were compared using the Mann–Whitney test. The distributions for the time to PSA nadir was compared using the log rank test. [ns: not significant].