Vaginal tolerance of CT based image-guided high-dose rate interstitial brachytherapy for gynecological malignancies

Table 2 Treatment details (n = 44)

	Median range
Central pelvic dose of EBRT^* (Gy)	30 (0-50)
No. of needles used in HDR-ISBT^†	15 (5-29)
HDR-ISBT^† fractions	4 (3-9)
HDR-ISBT^† dose per fraction (Gy)	6 (4-6)
CTV^†† (ml)	35.1 (2.4-142.1)
CTV^†† D₉₀ in EQD₂^\|\| (Gy)	67.7 (48.8-94.2)
Rectum D_2cc^¶ in EQD₂^\|\| (Gy)	60.8 (30.5-114.3)
Bladder D_2cc^¶ in EQD₂^\|\| (Gy)	58.1 (7.3-120.3)
Vaginal wall D_0.5cc^¶ in EQD₂^\|\| (Gy)	210.7 (51.5-468.1)
Vaginal wall D_1cc^¶ in EQD₂^\|\| (Gy)	167.3 (49.9-352.1)
Vaginal wall D_2cc^¶ in EQD₂^\|\| (Gy)	131.5 (43.7-294.4)
Vaginal wall D_4cc^¶ in EQD₂^\|\| (Gy)	111.6 (34.0-200.8)
Vaginal wall D_6cc^¶ in EQD₂^\|\| (Gy)	100.0 (20.4-173.7)
Vaginal wall D_8cc^¶ in EQD₂^\|\| (Gy)	83.2 (10.3-144.4)
Concurrent chemotherapy
Yes	10 patients
No	34 patients

^*EBRT: external beam radiation therapy.
^†HDR-ISBT: high-dose-rate interstitial brachytherapy.
^††CTV: clinical target volume.
^||EQD2: equivalent dose in 2 Gy fractions.
^¶D0.5cc, D1cc, D2cc, D4cc, D6cc, D8cc: most exposed 0.5, 1, 2, 4, 6 and 8 cm3 of tissue.

ISSN: 1748-717X