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Table 1 Freedom from new brain metastases at 6 months following radiosurgery

From: A new prognostic instrument to predict the probability of developing new cerebral metastases after radiosurgery alone

  Rates of freedom from new brain metastases (%) p
Radiosurgery dose   
  <20 Gy (N = 69) 60  
  20 Gy (N = 124) 61  
  >20 Gy (N = 21) 67 0.70
Age   
  ≤60 years (N = 99) 68  
  ≥61 years (N = 115) 56 0.49
Gender   
  Female (N = 112) 63  
  Male (N = 102) 60 0.51
ECOG performance score   
  0-1 (N = 158) 62  
  2 (N = 56) 62 0.75
Primary tumor type   
  Breast cancer (N = 21) 80  
  Non-small cell lung cancer (N = 72) 67  
  Malignant melanoma (N = 79) 54  
  Other tumors(N = 42) 57 0.10
Number of cerebral metastases   
  1 lesion <15 mm (N = 132) 70  
  1 lesion ≥15 mm (N = 55) 71  
  2 or 3 lesions (N = 82) 48 0.002
Location of cerebral metastases   
  Supratentorial alone (N = 179) 63  
  Infratentorial ± supratentorial (N = 35) 55 0.49
Extra-cerebral metastases   
  No (N = 88) 69  
  Yes (N = 126) 56 0.06
Time tumor diagnosis to radiosurgery   
  ≤15 months (N = 95) 63  
  >15 months (N = 119) 61 0.90
  1. ECOG = Eastern Cooperative Oncology Group.