Table 1 Freedom from new brain metastases at 6 months following radiosurgery
Rates of freedom from new brain metastases (%) | p | |
|---|---|---|
Radiosurgery dose | ||
<20 Gy (N = 69) | 60 | |
20 Gy (N = 124) | 61 | |
>20 Gy (N = 21) | 67 | 0.70 |
Age | ||
≤60 years (N = 99) | 68 | |
≥61 years (N = 115) | 56 | 0.49 |
Gender | ||
Female (N = 112) | 63 | |
Male (N = 102) | 60 | 0.51 |
ECOG performance score | ||
0-1 (N = 158) | 62 | |
2 (N = 56) | 62 | 0.75 |
Primary tumor type | ||
Breast cancer (N = 21) | 80 | |
Non-small cell lung cancer (N = 72) | 67 | |
Malignant melanoma (N = 79) | 54 | |
Other tumors(N = 42) | 57 | 0.10 |
Number of cerebral metastases | ||
1 lesion <15 mm (N = 132) | 70 | |
1 lesion ≥15 mm (N = 55) | 71 | |
2 or 3 lesions (N = 82) | 48 | 0.002 |
Location of cerebral metastases | ||
Supratentorial alone (N = 179) | 63 | |
Infratentorial ± supratentorial (N = 35) | 55 | 0.49 |
Extra-cerebral metastases | ||
No (N = 88) | 69 | |
Yes (N = 126) | 56 | 0.06 |
Time tumor diagnosis to radiosurgery | ||
≤15 months (N = 95) | 63 | |
>15 months (N = 119) | 61 | 0.90 |