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Table 2 mean measured and calculated doses for all films implanted subcutaneously in the cadaver, normalized to the prescription dose per fraction (4 Gy)

From: Hair-sparing whole brain radiotherapy with volumetric arc therapy in patients treated for brain metastases: dosimetric and clinical results of a phase II trial

 

VMAT-WBRT

OF-WBRT

Hair follicle subvolume

Film nr.

Depth (mm)

Measured dose (%)

Calculated dose 1 mm grid (%)

Calculated dose 4 mm grid (%)

Measureddose (%)

Calculated dose1 mm grid (%)

Calculated dose 4 mm grid (%)

Left

1

2.53

91.0

89.0

85.3

103.8

94.1

91.1

2

5.74

85.6

85.0

82.1

101.1

98.5

94.2

3

9.74

85.9

89.6

88.3

94.1

98.3

95.0

4

6.34

77.9

78.0

77.2

98.0

105.9

97.0

Mean

6.09

85.1

85.4

83.2

99.2

99.2

94.3

Right

5

11.65

94.5

85.0

82.9

97.9

103.9

96.7

6

6.73

96.5

91.0

89.0

94.9

99.8

95.8

7

8.8

90.2

81.7

81.1

98.5

102.9

97.0

Mean

9.06

93.7

85.9

84.4

97.1

102.2

96.5

Back

8

7.24

71.2

69.7

69.1

110.4

109.9

103.3

9

2.53

83.9

79.8

78.6

100.0

101.7

96.8

10

11.04

81.0

85.7

85.1

98.5

102.7

97.8

Mean

6.94

78.7

78.4

77.6

102.9

104.8

99.3

Top

11

4.68

75.2

70.4

64.2

114.2

111.8

91.5

12

2.02

84.3

81.1

70.4

112.3

111.4

89.4

13

2.03

51.1

59.7

56.9

111.9

108.9

99.7

Mean

2.91

70.2

70.4

63.9

112.8

110.7

93.5

All films

Mean

6.24

82.2

80.4

77.7

102.7

103.8

95.8

  1. The corresponding standard deviations, representing dose variations within each film, amounted to approximately 3.5% and 1.9% for the VMAT- and OF- films respectively. As the dose-volume-histograms for all detectors equally showed little dose variation within each film, further data analysis was uniquely based on the mean dose per film.