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Table 1 Summary of dose volume histogram analysis for GTV, brain stem and ipsilateral cochlea for VS patients

From: Critical appraisal of RapidArc radiosurgery with flattening filter free photon beams for benign brain lesions in comparison to GammaKnife: a treatment planning study

 

GK_1

GK_2

TB_1

TB_2

p

 

PTV vol [cm3]: 4.22 ± 2.85 Range: [1.20; 8.50]

Mean [Gy]

17.1 ± 0.9

17.1 ± 0.8

12.9 ± 0.1

16.0 ± 0.6

a, b, c, d

D2% [Gy]

22.7 ± 1.2

23.0 ± 0.8

13.4 ± 0.2

18.8 ± 1.1

a, b, c, d

D98% [Gy]

12.25 ± 0.0

12.25 ± 0.0

12.25 ± 0.0

12.25 ± 0.0

n.s.

St. dev [Gy]

2.7 ± 0.3

2.8 ± 0.2

0.3 ± 0.1

1.7 ± 0.3

a, b, c, d

Homogeneity [%]

51.7 ± 3.5

51.8 ± 1.2

6.4 ± 1.5

35.0 ± 4.9

a, b, c, d

PCI

0.81 ± 0.03

0.78 ± 0.04

0.83 ± 0.07

0.84 ± 0.04

c, d

PGI

2.7 ± 0.2

2.8 ± 0.2

5.1 ± 0.7

3.8 ± 0.6

a, b, c, d

DGM [cm]

0.4 ± 0.1

0.4 ± 0.1

0.6 ± 0.1

0.5 ± 0.1

a, b, c, d

 

Brain stem vol [cm 3 ] = 21.50 ± 8.37 Range: [8.69; 32.70]

D1cm3 [Gy]

5.1 ± 2.0

5.4 ± 2.2

5.7 ± 2.1

4.8 ± 1.6

n.s.

V8Gy [%]

1.9 ± 1.7

2.3 ± 1.8

2.5 ± 1.9

1.1 ± 1.0

a, b, d

V10Gy [%]

0.6 ± 0.5

0.8 ± 0.6

0.8 ± 0.7

0.2 ± 0.2

a, b, d

V12Gy [%]

0.1 ± 0.1

0.2 ± 0.2

0.03 ± 0.04

0.01 ± 0.01

a

 

Ipsilateral cochlea vol [cm 3 ] = 0.10 ± 0.01 Range: [0.02;0.13]

Mean [Gy]

6.6 ± 2.9

3.3 ± 0.8

5.5 ± 2.2

4.1 ± 0.9

a, b, c

D0.1cm3 [Gy]

4.0 ± 1.8

1.7 ± 1.0

3.1 ± 1.2

1.8 ± 0.5

a, b, c

D30% [Gy]

7.3 ± 3.2

3.6 ± 0.8

6.2 ± 2.4

4.7 ± 1.1

a, b, c, d

  1. Statistical significance p: a = GK_1 vs TB_1, b = GKv vs TB_2, c = GK_2 vs TB_1, d = GK_2 vs TV_2; n.s. = not significant. PCI = Paddick Conformity Index, PGI = Paddick Gradient Index, DGM = Dose Gradient measure. Dx% = Dose at x% of the volume.