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Table 4 Patients experienced severe (grade 3 or 4) toxicities by treatment group

From: Feasibility and efficacy of chemoradiotherapy for elderly patients with locoregionally advanced nasopharyngeal carcinoma: results from a matched cohort analysis

Toxicity CRT (%, N=101) RT (%, N=101) P
  Grade 3 Grade 4 All Grade 3 Grade 4 All  
Acute toxicity        
Leukopenia 12 (11.9) 0 (0) 12 (11.9) 0 (0) 0 (0) 0 (0) < 0.001
Granulocytopenia 17 (16.8) 0 (0) 17 (16.8) 0 (0) 0 (0) 0 (0) < 0.001
Thrombocytopenia 5 (5.0) 0 (0) 5 (5.0) 0 (0) 0 (0) 0 (0) 0.059
Anemia 6 (5.9) 0 (0) 6 (5.9) 1 (1.0) 0 (0) 1 (1.0) 0.118
Mucositis 52 (51.5) 1 (1.0) 53 (52.5) 38 (37.6) 0 (0) 38 (37.6) 0.034
Dermatitis 13 (12.9) 0 (0) 13 (12.9) 8 (7.9) 0 (0) 8 (7.9) 0.249
Hearing loss 1 (1.0) 0 (0) 1 (1.0) 0 (0) 0 (0) 0 (0) 1.000
Emesis 6 (6.0) 0 (0) 6 (6.0) 0 (0) 0 (0) 0 (0) 0.029
Hepatitis 2 (2.0) 0 (0) 2 (2.0) 2 (2.0) 0 (0) 2 (2.0) 1.000
Total any 65 (64.4) 1 (1.0) 66 (65.3) 44 (43.6) 0 (0) 44 (43.6) 0.002
Late toxicity        
Xerostomia 2 (2.0) 0 (0) 2 (2.0) 2 (2.0) 0 (0) 2 (2.0) 1.000
Ear (deafness/otitis) 8 (8.0) 0 (0) 8 (8.0) 9 (8.9) 0 (0) 9 (8.9) 0.800
Subcutaneous Fibrosis 6 (6.0) 0 (0) 6 (6.0) 8 (7.9) 0 (0) 8 (7.9) 0.580
Trismus 3 (3.0) 0 (0) 3 (3.0) 1 (1.0) 0 (0) 1 (1.0) 0.621
Total any 11 (10.1) 0 (0) 11 (10.1) 13 (12.9) 0 (0) 13 (12.9) 0.664