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Table 1 Subjects’ characteristics from 56 survivors of childhood ALL, according to CRT treatment

From: Cranial radiotherapy predisposes to abdominal adiposity in survivors of childhood acute lymphocytic leukemia

  Total Exposure to CRT p value
  No Yes
(n = 56) (n = 31) (n = 25)
Variable Count % Count % Count % Fisher’s exact test
Sex        0.590
Male 24 42.9 12 38.7 12 48.0  
Female 32 57.1 19 61.3 13 52.0  
GBTLI protocol        0.055
-85 9 16.1 3 9.7 6 24.0  
-93 35 62.5 18 58.1 17 68.0  
-99 12 21.4 10 32.2 2 8.0  
BMI Z score at ALL diagnosis        0.862
Normal 46 82.1 26 83.9 20 80.0  
Overweight 6 10.7 3 9.7 3 12.0  
Obese 1 1.8 0 0.0 1 4.0  
NA 3 5.4 2 6.4 1 4.0  
Variable Mean SD Min Max Mean SD Min Max Mean SD Min Max T -test
Age at ALL diagnosis (years) 7.5 3.9 2.1 17.0 7.4 4.0 2.1 17.0 7.5 3.8 2.3 13.8 0.958
Age at assessment (years) 18.6 2.5 15.0 22.9 18.0 2.5 15.0 22.9 19.4 2.3 15.0 22.8 0.034
Age at CRT (years) 8.0 4.0 2.6 14.4 .. .. .. .. 8.0 4.0 2.6 14.4 ..
Time post therapy (years) 8.5 3.5 2.5 16.4 8.1 3.5 2.5 14.9 9.0 3.4 2.6 16.4 0.350
Time since CRT (years) 11.4 3.8 4.0 18.7 .. .. .. .. 11.4 3.8 4.0 18.7 ..
BMI Z score at ALL diagnosis -0.28 1.38 -5.39 2.44 -0.61 1.44 -5.39 1.19 0.12 1.22 -2.30 2.44 0.055
  1. ALL Acute lymphocytic leukemia, CRT Cranial radiotherapy, GBTLI Brazilian Cooperative Group for Treatment of Childhood Acute Lymphocytic Leukemia, BMI Body mass index, NA Not available, SD Standard deviation, Min Minimum, Max Maximum.