Table 4 Comparison of observed clinical outcomes: IMRT-SIB cohort and published 3DCRT cohort[15]

SURVIVAL

median followup

952 days

570 days (19 months)

median DFS

not reached

690 days (23 months)

DFS (1 year)

88%

80%

DFS (2 years)

82%

44%

median OS

3 years (36 months)

1.8 years (21 months)

OS (1 year)

88%

65%

OS (2 years)

76%

38%

relapse: local

3 (17%)

0 (0%)

relapse: distant

7 (39%)

6 (40%)

TOXICITY

pulmonary toxicity (≤90 days)

4 (22%)

2 (15%)

esophageal toxicity (≤90 days)

9 (50%)

1 (7%)

pulmonary toxicity (>90 days)

5 (28%)

3 (20%)

esophageal toxicity (>90 days)

1 (6%)

2 (13%)