Table 4 Planning parameters specified in current treatment planning studies for passively scattered proton CSI
From: Standardized treatment planning methodology for passively scattered proton craniospinal irradiation
Planning Parameters | Â | Proton Planning Studies in the Literature | |||
|---|---|---|---|---|---|
Yuh et al.[10] | St. Clair et al.[7] | Yoon et al.[9] | Miralbell et al.[38] | Taddei et al.[8] | |
Number of Patients | 3 | 1 | 10 | 1 | 2 |
Patient Age (y) | 3 − 4 | 3.6 | 2 − 17 | 3 | 9,10 |
Cranial Field Orientation | RAO, LAO | RL, LL | RL, LL | None | RAO, LAO |
Spinal Fields: Number, Orientation | 1 − 3, PA | 1, PA | 1 − 3, PA | 1 | 2, PA |
Optimization | "restrict to disease site" | None stated | Proton plans re-normalized for comparison with Tomotherapy plans | constraint to achieve uniform dose to whole spinal theca | None stated |
Uncertainty Margins (cm) (with respect to clinical target) | Not given | 0.3 (Penumbra for 160Â MeV protons) | Proximal: 0.2 Distal: 0.2 Lateral: 1 Smear: 0.3 | 0.5 (symmetric around CTV) | Not given |