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Table 1 Patient demographics including volumes of organs of interest, for which each organ was contoured in its entirety *

From: Standardized treatment planning methodology for passively scattered proton craniospinal irradiation

Index Sex Age Thyroid Lungs Liver Kidneys Heart Esophagus Eyes Lens Spinal Cord Brain
(y) (cm3) (cm3) (cm3) (cm3) (cm3) (cm3) (cm3) (cm3) (cm3) (cm3)
1 F 2 1.9 320.8 372 63.5 139.5 1.2 16.2 0.3 41.4 1047
2 F 4 3.2 548.1 633.8 127 218.9 8.8 14.7 0.2 53.5 1336
3 F 6 3.3 1062 631.5 125.4 158.9 4.7 16.5 0.3 49.1 1456
4 F 8 4.5 1048 733.5 136.9 258.6 6.9 14.1 0.2 32.5 1402
5 F 9 3.8 1072 886.4 190.9 264 8.6 18.9 0.3 47.9 1318
6 M 3 1.5 457.9 595.9 137.8 96.6 5.5 12.3 0.1 19.5 1554
7 M 4 3.9 626.6 596 110 199.8 15.1 25.3 0.4 56.4 1380
8 M 6 4.1 814.8 847.4 160.8 214.5 5.3 16.6 0.2 83 1481
9 M 8 2.3 881.4 556.9 135.1 222.9 6.9 11.9 0.2 69.5 1471
10 M 9 5.4 1116 1066 117.4 276.9 7 10.8 0.2 48.4 1253
11 F 12 1.7 1479 646.4 169.4 243.1 8.7 12.8 0.2 26.9 1204
12 F 13 4.3 796.1 1429 198.1 227 13.6 14.9 0.1 32.5 1266
13* F 16 7.7 1850 1867 283.5 474.6 18.9 15.8 0.3 82.1 1279
14 M 12 11.7 1673 1354 287.2 434.2 15 14.2 0.1 111.1 1335
15*† M 13 12.6 2482 1498 342.5 417.4 18.6 16.5 0.2 42.3 1907
16 M 14 7.8 1247 1006 207.3 53.7 10.3 22.2 0.2 93.3 1533
17* M 15 10 2273 1816 356.6 493.1 18.3 15.2 0.1 110.9 1401
18* M 16 14.3 2308 1869 487.1 821.9 24 19.4 0.4 169.2 1542
Mean (cm3) 9.4 5.8 1225.3 1022.5 202.0 289.8 11.0 16.0 0.2 65.0 1397.8
SD (cm3) 4.5 3.9 636.5 479.9 105.6 176.3 6.0 3.5 0.1 36.7 177.3
  1. * Indicates patients whose target volume included the CSF and the entire vertebral bodies. All other patients’ target volumes included only the CSF.
  2. Patient was 13 years of age at the time of treatment, but assumed to be at skeletal maturity for treatment planning.
  3. Due poor contour resolution, volume estimates for the esophagus and thyroid of patient #1 were not optimal. However, sensitivity tests indicate that changes in the volumes for these organs by as much as 300% did not affect the mean values for the population.