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Table 2 Univariate analysis of prognostic factors of overall survival (n = 83)

From: Three-dimensional conformal radiotherapy with concurrent chemotherapy for postoperative recurrence of esophageal squamous cell carcinoma: clinical efficacy and failure pattern

Variable HR, 95% CI p value
Sex (male vs. female) 0.70 (0.26-1.89) 0.477
Age (>55 yrs vs. ≤55 yrs) 0.67 (0.28-1.57) 0.344
ECOG performance status (0–1 vs. 2–3) 0.72 (0.27-1.86) 0.523
Primary tumor location (Upper vs. Middle vs. Lower) 0.80 (0.40-1.61) 0.533
Radical surgery (Two-field vs. three-field) 1.31 (0.55-3.12) 0.540
Histology of primary tumor (G1-2 vs. G3-4) 1.05 (0.51-2.13) 0.905
Stage of primary tumor (I-II stage vs. III stage) 1.66 (0.88-3.12) 0.120
Time between surgery and RT (>14 mon vs. ≤14 mon) 0.77 (0.34-1.77) 0.538
Recurrence site (AR vs. LR) 2.70 (1.06-6.88) 0.028 *
RT dose(>60 Gy vs. ≤60 Gy) 1.26 (0.47-3.35) 0.648
Concurrent chemotherapy (PF vs. TP) 0.58 (0.31-1.09) 0.090 #
Tumor response after CCRT (CR vs. non-CR) 4.20 (2.04-8.65) 0.000 *
  1. Note: *Univariate analysis showed that tumor response after CCRTand recurrence site had significant associations with OS. # Univariate analysis showed that concurrent chemotherapy showed a trend of association with OS.