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Table 3 Comparison of normal tissue radiation exposure pre- and post-induction chemotherapy

From: Quantitative analysis of tumor shrinkage due to chemotherapy and its implication for radiation treatment planning in limited-stage small-cell lung cancer

  

Pre-chemo plan

Post-chemo plan

p-value

Lung

    
 

V5 (%)

59.0 ± 6.4

54.8 ± 6.0

0.000

 

V20 (%)

32.3 ± 5.1

28.2 ± 4.0

0.000

 

MLD (Gy)

18.6 ± 2.3

15.5 ± 1.9

0.000

Heart

    
 

V30 (%)

24.2 ± 21.0

17.1 ± 17.0

0.001

 

Mean (Gy)

18.0 ± 11.0

13.7 ± 9.0

0.000

 

Max (Gy)

64.3 ± 10.9

61.5 ± 10.1

0.263

Esophagus

    
 

V40 (%)

45.4 ± 20.0

39.6 ± 16.6

0.023

 

V50 (%)

39.1 ± 22.8

33.1 ± 17.8

0.038

 

V60 (%)

27.6 ± 21.1

20.2 ± 14.3

0.022

 

AV60 (cm3)

8.7 ± 5.9

6.7 ± 5.0

0.012

 

Mean (Gy)

31.9 ± 10.6

28.4 ± 8.7

0.004

 

Max (Gy)

65.2 ± 3.0

65.0 ± 2.7

0.688

  1. Abbreviations: AV60 Absolute volume > 60Gy.
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Radiation Oncology

ISSN: 1748-717X

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