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Table 3 EPIC scores (± SE) at each time point

From: A randomized hypofractionation dose escalation trial for high risk prostate cancer patients: interim analysis of acute toxicity and quality of life in 124 patients

Time points

Baseline

1 month

2 months

3 months

p-value (ANOVA)

Arm

1/2

1

2

1

2

1

2

N

=124

=55

=67

=54

=56

=51

=54

 

Urinary domain

91.9

84.3 (2.0)

81.0 (1.9)

81.9 (2.0)

81.7 (2.2)

87.5 (1.8)

91.1 (1.8)

0.5470

Function

97.5

91.3 (1.7)

92.1 (1.5)

91.6 (18)

90.6 (1.8)

95.3 (1.6)

95.4 (1.5)

0.8058

Bother

87.9

79.4 (2.5)

73.0 (2.6)

75.0 (2.6)

75.4 (3.0)

82.0 (2.4)

87.9 (2.4)

0.4913

Incontinence

97.1

94.8 (1.4)

93.8 (1.5)

93.7 (1.6)

91.7 (2.1)

96.6 (1.6)

95.6 (1.7)

0.8293

Irritative/obstructive

89.5

79.2 (2.6)

74.7 (2.5)

76.5 (2.6)

77.0 (2.8)

83.3 (2.3)

88.1 (2.3)

0.4556

Bowel domain

95.8

82.7 (2.7)

80.1 (2.5)

84.1 (2.8)

78.1 (3.2)

89.7 (2.6)

92.6 (1.7)

0.9208

Function

95.6

82.3 (2.6)

77.1 (2.6)

83.7 (3.0)

76.6 (3.2)

89.3 (2.8)

91.0 (2.1)

0.7569

Bother

95.8

82.7 (2.7)

80.1 (2.5)

84.1 (2.8)

78.1 (3.2)

89.7 (2.6)

92.6 (1.7)

0.9208

N

=121

=53

=66

=53

=55

=50

=53

 

Sexual domain

28.6

22.1 (2.4)

22.0 (2.9)

26.1 (3.0)

26.1 (3.1)

23.2 (3.2)

24.2 (3.4)

0.3919

Function

16.0

8.6 (2.8)

8.1 (3.2)

11.1 (3.2)

11.3 (3.4)

9.5 (3.3)

10.4 (3.9)

0.6457

Bother

56.9

52.4 (5.0)

53.2 (4.9)

59.9 (5.9)

59.4 (6.3)

54.0 (5.7)

55.3 (6.0)

0.3805

Hormonal domain

83.9

83.6 (1.8)

84.7 (1.3)

86.2 (1.8)

83.5 (2.0)

85.1 (2.2)

86.5 (1.9)

0.9304

Function

75.9

76.0 (2.7)

77.7 (2.4)

79.0 (2.6)

75.4 (3.6)

77.3 (2.9)

80.6 (2.6)

0.9012

Bother

90.5

90.0 (1.3)

90.5 (1.1)

92.3 (1.5)

90.2 (1.6)

91.7 (2.0)

91.5 (2.0)

0.7273

  1. Abbreviations: Arm 1 = conventional fractionation; Arm 2 = hypofractionation; N = number of patients.