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Table 4 Nonhematologic toxicity

From: Dose escalation of accelerated hypofractionated three-dimensional conformal radiotherapy (at 3 Gy/fraction) with concurrent vinorelbine and carboplatin chemotherapy in unresectable stage III non-small-cell lung cancer: a phase I trial

Toxicity 66 Gy 69 Gy 72 Gy Total
Case Case Case Case (%)
Radiation pneumonia     10(76.9)
I 1 2 1  
II 1 2 2  
III 0 0 1  
Radiation oesophagitis     11(84.6)
I 1 2 1  
II 1 3 1  
III 0 0 2  
Radiation dermatitis     9(69.2)
I 1 3 3  
II 0 1 1  
Nausea     12(92.3)
I 1 2 1  
II 1 2 1  
III 1 1 2  
Vomiting     8(61.5)
I 1 1 2  
II 1 1 1  
III 0 1 0  
Anorexia     12(92.3)
I 1 1 1  
II 2 2 1  
III 0 2 2  
Fatigue     11(84.6)
I 0 3 1  
II 1 2 2  
III 1 0 1  
ALTI 0 1 2 3(23.1)
ASTI 1 0 2 3(23.1)
Cr I 1 0 1 2(15.4)
BIL I 0 1 0 1(7.7)
  1. ALT: alanine aminotransferase; AST: aspartate aminotransferase; Cr: serum creatinine; BIL: bilirubin.