Prostate volume changes during permanent seed brachytherapy: an analysis of intra-operative variations, predictive factors and clinical implication

Table 3 Univariate and multivariate regression analysis for volume difference

Modeled with edema between	Factor	Univariate analysis		Multivariate analysis
Modeled with edema between	Factor	Correlation coefficient (95% CI)	P value*	Correlation coefficient (95% CI)	P value
∆ V2 - V1	Baseline volume	−0.18 (−0.27/-0.10)	<0.0001	−0.18 (−0.27/-0.10)	<0.0001
∆ V2 - V1	Age	−0.05 (−0.19/0.07)	0.38	−0.005 (−0.13/0.12)	0.94
∆ V3 - V1	Baseline volume	−0.16 (−0.25/-0.07)	<0.001	−0.16 (−0.26/-0.07)	0.001
∆ V3 - V1	Age	−0.05 (−0.19/0.10)	0.51	−0.001 (−0.15/0.14)	0.99
∆ V3 – V2	Baseline volume	0.024 (−0.02/0.07)	0.30	0.006 (−0.05/0.06)	0.82
	Age	0.006 (−0.06/0.07)	0.85	−0.002 (−0.07/0.07)	0.94
	Seeds/needles	−0.19 (−1.46/1.09)	0.77	-	-
	Activity	−0.52 (−1.35/0.30)	0.21	−0.11 (−1.3/1.06)	0.84
	No. of seeds	0.03 (−0.002/0.06)	0.07	0.03 (−0.01/0.07)	0.18
	No. of needles	0.12(0.018/0.23)	0.02	0.11 (−0.05/0.28)	0.16

Abbreviations: CI confidence intervals, ∆ 2–1 difference between volumes 2 and 1, ∆ 3-2 difference between volumes 3 and 2, ∆ 3-1 difference between volumes 3 and 1, SD standard deviation, IQR interquartile range. * bold when p < 0.05.

ISSN: 1748-717X