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Table 4 Survival estimates and patterns of failure at 2 years post CRT

From: Oropharyngeal squamous cell carcinoma with known human papillomavirus status treated with definitive chemoradiotherapy: patterns of failure and toxicity outcomes

Outcome at 2 years post CRT

HPV-positive (95% CI)

HPV-negative (95% CI)

p-value

Locoregional recurrence

3.3% (0–6.9)

26.3% (6.0-46.6)

0.002

Distant recurrence

2.8% (0–6.9)

4.8% (0–13.9)

0.98

Overall survival

93.9% (87.9-100)

73.2% (52.3-94.2)

0.002

Disease free survival

92.7% (86.9-98.5)

63.5% (42.8-84.1)

0.001