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Table 1 Characteristics of 64 patients treated for recurrent high-grade gliomas using a second series of radiotherapy with or without concurrent chemotherapy

From: Reirradiation in progressive high-grade gliomas: outcome, role of concurrent chemotherapy, prognostic factors and validation of a new prognostic score with an independent patient cohort

Characteristic

 

Median age at Re-RT (years)

53.5

Range: age at Re-RT (years)

21.8 – 81.1

< 50 years at Re-RT

26/64 (40.6%)

≥ 50 years at Re-RT

38/64 (59.4%)

Male

34/64 (53.1%)

Female

30/64 (46.9%)

WHO IV

53/64 (82.8%)

WHO III

11/64 (17.2%)

Karnofsky performance score < 70

13/64 (20.3%)

Karnofsky performance score ≥ 70

51/64 (79.7%)

Median time (RT to Re-RT) (months)

13.4

Range: time (RT to Re-RT) (months)

2.7 – 202.6

Time from RT to Re-RT ≤ 12 months

21/64 (32.8%)

Time from RT to Re-RT > 12 months

43/64 (67.2%)

Concurrent chemotherapy

36/64 (56.3%)

Carboplatin/etoposide

24/64 (37.5%)

Temozolomide

12/64 (18.8%)

Complete resection before Re-RT

8/64 (12.5%)

Incomplete/no resection before Re-RT

56/64 (87.5%)