Radiation Oncology

Table 2 Comparison of PSPT vs. IMRT, IMPT vs. IMRT, and IMPT vs. IMRT for three lung volumes: total lung (minus PTV), contralateral lung, and ipsilateral lung

From: An in-silico comparison of proton beam and IMRT for postoperative radiotherapy in completely resected stage IIIA non-small cell lung cancer

		PSPT vs. IMRT		IMPT vs. IMRT		IMPT vs. PSPT
		*∆ (%)*	*p value*	*∆ (%)*	*p value*	*∆ (%)*	*p value*
Total lung	V5	−22.8	0.002	−41.7	<0.001	−24.5	0.001
	V10	−8.6	0.2	−37.3	<0.001	−31.4	<0.001
	V20	2.9	0.7	−34.5	<0.001	−36.4	<0.001
	V30	22.1	0.005	−26.2	0.001	−39.6	<0.001
	Mean (cGy)	−7.3	0.2	−38.4	<0.001	−33.5	<0.001
Contralateral lung	V5	−29.4	<0.001	−52.8	<0.001	−33.1	<0.001
	V10	22.1	0.006	−26.2	0.001	−39.6	<0.001
	V20	−1.7	0.8	−42.5	<0.001	−41.5	0.002
	V30	15.7	0.009	−27.5	0.03	−37.3	<0.001
	Mean (cGy)	−17.1	0.006	−47.3	<0.001	−36.4	<0.001
Ipsilateral lung	V5	−13.5	0.02	−26.1	<0.001	−14.6	0.007
	V10	−5.8	0.3	−25.6	<0.001	−21.0	<0.001
	V20	5.1	0.4	−23.9	<0.001	−27.6	<0.001
	V30	18.8	0.007	−19.4	0.009	−32.1	<0.001
	Mean (cGy)	2.3	0.6	−23.9	<0.001	−25.6	<0.001

Delta represents change of first technique listed versus baseline comparison technique (second listed).

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ISSN: 1748-717X

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