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Table 3 DVH analysis for PTV and healthy tissue for treatment plans created with FF and FFF beams

From: The impact of flattening-filter-free beam technology on 3D conformal RT

Parameter

Breast

Neurocranium

Lung PTV

Spine metastasis

Prostate

n

13

11

7

10

11

Volume [cm3]

922.7 ± 239.4

1329.3 ± 109.3

501.9 ± 318.0

175.7 ± 79.6

211.3 ± 94.9

Mean+SD [Gy]

50.2 ± 0.3

30.9 ± 0.3

50.3 ± 0.2

37.9 ± 0.4

66.6 ± 0.6

50.2 ± 0.4

30.3 ± 0.2

50.5 ± 0.4

38.0 ± 0.3

66.5 ± 0.6

p

0.495

0.000

0.408

0.230

0.622

V95 [%]

89.8 ± 1.6

99.9 ± 0.0

95.4 ± 3.3

98.3 ± 3.3

99.6 ± 0.3

89.1 ± 1.8

99.4 ± 0.3

94.3 ± 2.4

97.7 ± 2.6

99.2 ± 0.3

p

0.166

0.000

0.120

0.280

0.027

V107 [%]

0.0 ± 0.0

0.0 ± 0.0

0.0 ± 0.0

0.0 ± 0.0

0.0 ± 0.0

0.0 ± 0.0

0.0 ± 0.0

0.1 ± 0.3

0.0 ± 0.0

0.0 ± 0.0

p

0.166

0.000

0.234

0.133

0.459

HI

0.15 ± 0.0

0.06 ± 0.0

0.12 ± 0.0

0.10 ± 0.0

0.08 ± 0.0

 

0.17 ± 0.0

0.08 ± 0.0

0.13 ± 0.0

0.11 ± 0.0

0.09 ± 0.0

p

0.000

0.000

0.151

0.027

0.023

   

Healthy tissue

  

V5Gy [%]

7.8 ± 1.1

54.7 ± 10.0

27.6 ± 9.5

10.4 ± 2.4

19.8 ± 8.3

7.7 ± 1.1

54.3 ± 10.0

27.7 ± 8.0

10.2 ± 2.4

20.0 ± 8.2

p

0.006

0.000

0.921

0.341

0.639

V10Gy [%]

6.2 ± 1.0

50.8 ± 9.4

20.0 ± 7.3

6.2 ± 1.7

14.4 ± 6.7

6.2 ± 1.0

50.4 ± 9.4

19.6 ± 6.4

6.1 ± 1.7

14.6 ± 6.5

p

0.963

0.000

0.553

0.202

0.293

  1. FFF results are in bold. VxGy: volume receiving at least x Gy. Vx: volume receiving at least x % of the prescribed dose. Dx %: dose received by at least x % of the volume. Statistical significance is defined for p < 0.01.