|
Site of failure
| |
Pre-op CRT, n(%)
|
Post-op CRT, n(%)
|
P
‡
|
|---|
|
Type of recurrence
|
LR alone
|
17 (13.4)
|
8 (8.1)
|
0.573
|
| |
LR with DM
|
21 (16.5)
|
15 (15.2)
| |
| |
DM alone
|
89 (70.1)
|
76 (76.8)
| |
| |
Total
|
127 (100)
|
99 (100)
| |
|
DM site*
|
Lung
|
64 (48.1)
|
44 (37.9)
|
0.208
|
| |
Liver
|
24 (18.0)
|
30 (25.9)
| |
| |
PAN
|
27 (20.3)
|
20 (17.2)
| |
| |
Others†
|
18 (13.5)
|
22 (19.0)
| |
| |
Total
|
133 (100)
|
116 (100)
| |
|
Time to failure
| |
Pre-op CRT, months
|
Post-op CRT, months
|
P
‡
|
|
Type of recurrence
|
LR alone
|
37.2 ± 21.2
|
35.2 ± 27.4
|
0.841
|
| |
LR with DM
|
25.6 ± 21.3
|
19.9 ± 13.3
|
0.372
|
| |
DM alone
|
21.2 ± 15.9
|
19.1 ± 12.1
|
0.334
|
| |
Total
|
24.1 ± 18.3
|
20.5 ± 14.5
|
0.112
|
|
DM site*
|
Lung
|
24.3 ± 18.2
|
20.1 ± 10.7
|
0.130
|
| |
Liver
|
16.5 ± 9.3
|
18.2 ± 14.1
|
0.597
|
| |
PAN
|
18.8 ± 16.6
|
19.0 ± 13.5
|
0.964
|
| |
Others†
|
21.5 ± 15.4
|
18.3 ± 13.9
|
0.494
|
- Abbreviations: CRT = chemoradiotherapy; LR = local recurrence; DM = distant metastasis; PAN = para-aortic lymph node.
- *Some patients had distant metastases occurring at multiple sites.
- †Peritoneal seeding, inguinal lymph node, bone, brain, supraclavicular lymph node.
- ‡Linear-by-linear association or t- test.
