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Table 1 Calculation of survival parameters based on proliferation assay using the equation Survival = E x p − α D o s e − β D o s e 2

From: Increased Artemis levels confer radioresistance to both high and low LET radiation exposures

A. Survival parameters for 293Art Artemis over-expressing Cells

Radiation Type

α, Gy −1

β, Gy −2

D 37 , Gy

Fold

293Art/HEK293c

X-rays

–

0.057 ± 0.002

4.21 ± 0.087

1.7

Titaniuma

0.47 ± 0.02

0.034 ± 0.008

1.86 ± 0.024

2.2

Ironb

0.22 ± 0.002

0.065 ± 0.007

2.59 ± 0.074

3.0

B. Survival parameters for 293 Wild type Cells

Radiation Type

α, Gy −1

β, Gy −2

D 37 , Gy

X-rays

0.287 ± 0.033

0.048 ± 0.006

  

Titaniuma

0.025 ± 0.044

–

  

Ironb

1.11 ± 0.29

0.086 ± 0.075

0.85 + 0.15