Table 2 Comparison of available studies in the literature

Katz et al., 2007 [21]

69

30-55/2-6

40-73*

0.1-950*

14.5

76

McCammon et al., 2009 [5]

81

3 dose levels:

3 levels*:

2.8-370

8.2

1.) < 36/12

1.) 39

1.) 40

2.) 36-54/12-18

2.) 39-58

2.) 88

3.) 54/18

3.) 58

3.) 100

Milano et al., 2008 [22]

121

10-20/10-20

16-50

0.2-422

Not stated

57

Goodmann et al., 2010 [23]

40

18-30/18-30

42-100*

0.8-146

17

77

Iwata et al., 2010 [24]

12

50-55/5-5.5

62-71*

0.9-22*

14.5

86

Rusthoven et al., 2009 [25]

63

36-60/12-20

66-150*

<113*

16

95

Lee et al., 2009 [26]

68

42-60/7-10

59-100*

1.19-3000

10.8

71

Current series JBH et al.

22

24-60/24-12

44-150

11-419

12

57