Figure 6
From: Vascular responses to radiotherapy and androgen-deprivation therapy in experimental prostate cancer
Correlations between parameters from dynamic contrast-enhanced MRI and quantitative immunohistochemistry. Correlations between DCE MRI parameters from ( A) semi-quantitative and ( B) Tofts kinetic analysis, and qIHC parameters. Color labeling reflects correlation strength (Pearson correlation coefficients), as indicated in the color scale (top). Positive and negative correlations are indicated with + and –, respectively, and encircled + and – denotes significant correlations ( p < 0.05). Abbreviations: AUC; area under the relative signal intensity ( RSI) curve, VS; mean vessel size (μm2), VD; vessel density (number of vessels/mm2), VF; vessel area fraction, PF; perfused area fraction, DHV; distance from hypoxia to vessels (μm), NF; necrotic fraction, HF; hypoxic fraction, AHS; acute hypoxia score\.