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Table 2 Univariate analysis of functional and standard dosimetric parameters association with radiation-induced lung injury (RILI)

From: Functional dosimetric metrics for predicting radiation-induced lung injury in non-small cell lung cancer patients treated with chemoradiotherapy

Parameters aCut-off value RILI rate (%) p value
FV5 / V5 0.80 / 0.70 b5.3:c47.4 /b5.4: c45.0 0.001 / 0.001
FV10 / V10 0.45 / 0.56 5.4: 45.0 / 5.1: 50.0 0.001 / 0.001
FV15 / V15 0.40 / 0.40 2.9: 43.5 / 0.0: 39.3 0.001 / 0.001
FV20 / V20 0.30 / 0.32 5.6: 42.9 / 3.2: 38.5 0.001 / 0.001
FV25 / V25 0.28 / 0.26 9.1: 53.8 / 5.9: 39.1 0.001 / 0.004
FV30 / V30 0.21 / 0.21 7.7: 44.4 / 8.6: 36.4 0.002 / 0.015
FV35 / V35 0.15 / 0.17 7.3: 50.0 / 7.9: 42.1 0.001 / 0.004
FV40 / V40 0.14 / 0.17 7.1: 53.3 / 7.1: 31.0 0.001 / 0.041
FV45 / V45 0.11 / 0.13 7.1: 53.3 / 9.7: 30.8 0.001 / 0.089
FV50 / V50 0.07 / 0.11 7.1: 53.3 / 12.8: 37.5 0.001 / 0.061
FV55 / V55 0.06 / 0.08 9.5: 50.0 / 15.8: 31.3 0.003 / 0.270
FV60 / V60 0.04 / 0.03 10.0: 43.8 / 15.0:22.6 0.008 / 0.721
  1. Note: functional dosimetric parameters associated with RILI were typed with bold.
  2. a Cut-off value was optimized by receiver operating characteristic curve.
  3. b RILI rate calculated when Vx < cut-off value.
  4. c RILI rate calculated when Vx ≥ cut-off value.