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Table 2 Univariate analysis of functional and standard dosimetric parameters association with radiation-induced lung injury (RILI)

From: Functional dosimetric metrics for predicting radiation-induced lung injury in non-small cell lung cancer patients treated with chemoradiotherapy

Parameters

aCut-off value

RILI rate (%)

p value

FV5 / V5

0.80 / 0.70

b5.3:c47.4 /b5.4: c45.0

0.001 / 0.001

FV10 / V10

0.45 / 0.56

5.4: 45.0 / 5.1: 50.0

0.001 / 0.001

FV15 / V15

0.40 / 0.40

2.9: 43.5 / 0.0: 39.3

0.001 / 0.001

FV20 / V20

0.30 / 0.32

5.6: 42.9 / 3.2: 38.5

0.001 / 0.001

FV25 / V25

0.28 / 0.26

9.1: 53.8 / 5.9: 39.1

0.001 / 0.004

FV30 / V30

0.21 / 0.21

7.7: 44.4 / 8.6: 36.4

0.002 / 0.015

FV35 / V35

0.15 / 0.17

7.3: 50.0 / 7.9: 42.1

0.001 / 0.004

FV40 / V40

0.14 / 0.17

7.1: 53.3 / 7.1: 31.0

0.001 / 0.041

FV45 / V45

0.11 / 0.13

7.1: 53.3 / 9.7: 30.8

0.001 / 0.089

FV50 / V50

0.07 / 0.11

7.1: 53.3 / 12.8: 37.5

0.001 / 0.061

FV55 / V55

0.06 / 0.08

9.5: 50.0 / 15.8: 31.3

0.003 / 0.270

FV60 / V60

0.04 / 0.03

10.0: 43.8 / 15.0:22.6

0.008 / 0.721

  1. Note: functional dosimetric parameters associated with RILI were typed with bold.
  2. a Cut-off value was optimized by receiver operating characteristic curve.
  3. b RILI rate calculated when Vx < cut-off value.
  4. c RILI rate calculated when Vx ≥ cut-off value.