ANOVA of mean variances


Sample

M_{Var}

Sample

M_{Var}

Fvalue

pvalue


0Gy (I)

47.63

0Gy (II)

83.81

2.493

0.153

0Gy (I)

47.63

0Gy (III)

23.03

2.551

0.149

0Gy (II)

83.81

0Gy (III)

23.03

11.624

0.009

4Gy (I)

86.53

4Gy (II)

284.02

23.365

0.001

4Gy (I)

86.53

4Gy (III)

106.01

1.807

0.216

4Gy (II)

284.02

4Gy (III)

106.01

9.506

0.002

0Gy (I)

47.63

4Gy (I)

86.53

4.328

0.071

0Gy (II)

83.81

4Gy (II)

284.02

21.728

0.002

0Gy (III)

23.03

4Gy (III)

106.01

70.647

<0.001

4Gy (I)

86.53

4Gy+15min (I)

48.96

10.140

0.013

4Gy (I)

86.53

4Gy+45min (I)

31.92

20.575

0.002

4Gy+15min (I)

48.96

4Gy+45min (I)

31.92

9.887

0.014

2x4Gy (IV)

120.51

2x4Gy+15min (IV)

138.36

0.947

0.359

2x4Gy (IV)

120.51

2x4Gy+45min (IV)

67.67

31.585

<0.001

2x4Gy+15min (IV)

138.36

2x4Gy+45min (IV)

67.67

14.608

0.005

2x4Gy (IV)

120.51

4Gy (I)

86.53

6.839

0.031

2x4Gy+15min (IV)

138.36

4Gy+15min (I)

48.96

26.039

0.001

2x4Gy+45min(IV)

67.67

4Gy+45min (I)

31.92

19.795

0.002

 Analysis of variance (ANOVA) was performed for the following pairs (1.6.) of fraction IIV^{*}. (1.) Influence of DNA structure, antioxidants on heterogeneity of DNA damage without irradiation (line 1–3) and (2.) with irradiation (line 4–6). (3.) Influence of different radiation doses (line 7–9), (4.) heterogeneity of samples with increasing repair periods after single (line 10–12) and double fractionated irradiation (line 13–15) and (6.) comparison of single vs. double fractionated irradiation after same repair periods (line 16–18). In brief, heterogeneity was always significantly increased in histone and antioxidantdepleted cells (fraction II) and after single or double fractionated irradiation but decreased with repair time or addition of antioxidants. Related mean variance (five donors) and mean DNA damage were shown in Figure 3a
 Abbreviations: F = Fvalue, p = probability value. M_{Var} = mean variance.
 ^{*} 200 leukocytes/sample of each donor were measured for calculation of DNA damage in %Tail DNA and variance. Mean variance was calculated from 5 donors.