Head and neck region consolidation radiotherapy and prophylactic cranial irradiation with hippocampal avoidance delivered with helical tomotherapy after induction chemotherapy for non-sinonasal neuroendocrine carcinoma of the upper airways

Franco, Pierfrancesco; Numico, Gianmauro; Migliaccio, Fernanda; Catuzzo, Paola; Cante, Domenico; Ceroni, Paola; Sciacero, Piera; Carassai, Pierpaolo; Canzi, Paolo; La Porta, Maria Rosa; Girelli, Giuseppe; Borca, Valeria Casanova; Pasquino, Massimo; Tofani, Santi; Ozzello, Franca; Ricardi, Umberto

doi:10.1186/1748-717X-7-21

Table 1 Dosimetric parameters overview

From: Head and neck region consolidation radiotherapy and prophylactic cranial irradiation with hippocampal avoidance delivered with helical tomotherapy after induction chemotherapy for non-sinonasal neuroendocrine carcinoma of the upper airways

OARs	Dosimetric constraints	Dosimetric results
R hippocampus	D_max < 6 Gy V_{3 Gy} < 20%	D_max 9,9 Gy	D_mean 6,5 Gy
			Median dose 6,3 Gy
L hippocampus	D_max < 6 Gy V_{3 Gy} < 20%	D_max 10,0 Gy	D_mean 6,5 Gy
			Median dose 6,2 Gy
R HAV	D_max < 25 Gy V_{20 Gy} < 20%	D_max 22,4 Gy	V_{20 Gy} 2,00%
L HAV	D_max < 25 Gy V_{20 Gy} < 20%	D_max 23,5 Gy	V_{20 Gy} 3,00%
R lens	D_max < 6 Gy	D_max 4,8 Gy
L lens	D_max < 6 Gy	D_max 4,7 Gy
R ocular bulb	D_max < 54 Gy D_mean < 35 Gy	D_max 17,8 Gy	D_mean 6,8 Gy
L ocular bulb	D_max < 54 Gy D_mean < 35 Gy	D_max 15,6 Gy	D_mean 6,3 Gy
R optic nerve	D_max < 54 Gy	D_max 25,9 Gy
L optic nerve	D_max < 54 Gy	D_max 25,6 Gy
Optic chiasm	D_max < 54 Gy	D_max 28,3 Gy
Spinal cord	D_max < 45 Gy	D_max 28,6 Gy
Brainstem	D_max < 54 Gy	D_max 39,4 Gy
Oral cavity	D_mean < 45 Gy	D_mean 40,7 Gy
R cochlea	D_mean < 35 Gy	D_mean 38,1 Gy
L cochlea	D_mean < 35 Gy	D_mean 35,1 Gy
Pituitary gland	D_max < 40 Gy D_mean < 35 Gy	D_max 29,9 Gy	D_mean 28,1 Gy
Glottic larynx	D_mean < 50 Gy V_{60 Gy} < 45%	D_mean 58,7 Gy	V_{60 Gy} 47,00%
Mandible	D_max < 70 Gy D_mean < 60 Gy	D_max 60,5 Gy	D_mean 45,6 Gy
R parotid	D_mean < 26 Gy V_{30 Gy} < 50%	D_mean 28,0 Gy	V_{30 Gy} 35,50%
L parotid	D_mean < 26 Gy V_{30 Gy} < 50%	D_mean 25,9 Gy	V_{30 Gy} 28,50%
R brachial plexus	D_max < 55 Gy	D_max 50,6 Gy
L brachial plexus	D_max < 55 Gy	D_max 49,5 Gy
R lung	V_{45 Gy} < 33%	V_{45 Gy} 1,00%
L lung	V_{45 Gy} < 33%	V_{45 Gy} 1,50%
Thyroid	V_{30 Gy} < 50%	V_{30 Gy} 67,00%
R TMJ	D_max < 70 Gy D_mean < 60 Gy	D_max 45,6 Gy	D_mean 27,0 Gy
L TMJ	D_max < 70 Gy D_mean < 60 Gy	D_max 44,0 Gy	D_mean 28,2 Gy

OARs organs at risk; R right; L left; TMJ temporo-mandibular joint

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ISSN: 1748-717X

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