Table 1 Overview of important in vivo and in vitro studies (with either a large number of CIEDs or interesting findings, excluding reviews)
Year | First author | Study type | Number of PM included | Number of ICD included | Intervention: Max Dose in study(Gy) | Number of defects | type of defect |
|---|---|---|---|---|---|---|---|
2010 | Ferrara | Prospective in vivo | 37 | 8 | < 2,5 | No defects | No defects |
2010 | Wadasadawala | Review+ 8 pacemakers | 8 | 0 | 60 | No defects | No defects |
2009 | Zweng | case report | 1 | 0 | 0.11 | 1[1] @ 0.11 Gy | runaway PM |
2009 | Gelblum | Retrospective in vivo | 0 | 33 | <3 | 1[33] @3 Gy | Reset to factory settings |
2008 | Lau | case report | 0 | 1 | <0,15 | 1[1] @ 0,15 Gy | electrical reset |
2008 | Kapa | in vitro research + in vivo retrospective | 7 (in vivo) | 20 (in vitro) 5 (in vivo) | < 4 (in vitro) unreported for in vivo | No defects | No defects, 4 devices relocated before RT |
2008 | Munshi[52] | case report | 1 | Â | 4.3 | No defects | No defects |
2007 | Nemec | case report | 0 | 1 | < 6 | 1[1] @ <1 Gy* | Runaway ICD |
2005 | Hurkmans[24] | in vitro research | 19 | 0 | < 120 | Output, sense and communication | |
2005 2006 | Hurkmans Uiterwaal[24] | in vitro research | 0 | 11 | < 120 | To low shock energy, sensing and Battery charge time, erroneous VF or VT detection. | |
2004 | John | case report | 0 | 1 | 50 | 1[1] @ not reported dose | shock impedance (coil failure) |
2002 | Mouton | in vitro research | 96 | 0 | 200 | 4(96) @ 0,2 Gy 21(96)@2 Gy >0.2 Gy/min | 8 defect modes described |
2001 | Niehaus | Review+ in vivo research | 0 | 3 | < 5 | no defects | No defects |
2000 | Tsekos | case report | 1 | 0 | < 50 | 1[1] @ not reported dose | Decrease of battery load |
1994 | Souliman | in vitro research | 18 | 0 | 70 | 1) temporary change to interference or safety mode pacing lasting for the duration of the irradiation only[2] change to interference mode pacing—from which recovery may occur after reprogramming the pacemaker[3] severe damage | |
1994 | Wilm[53] | in vitro research | 20 | 0 | 300 | 2[20] @ 10 Gy (complete defects) | Complete defect, decrease of pace amplitude, loss of telemetry |
1991 | Rodriguez | in vitro research | 23 | 4 | < 50 | sensitivity, telemetry and total defect |