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Table 1 Patient, tumour, and treatment characteristics

From: Conservative treatment of breast ductal carcinoma in situ: results of an Italian multi-institutional retrospective study

Age Median 55 years  
  Range 29-84 years  
Menopausal status Pre- or peri-menopause 181 31%
  Menopause 395 67%
  Unknown 10 2%
Diagnosis modalities Mammography alone 387 66%
  Clinical signs and mammography 176 30%
  Clinical signs alone 23 4%
Mammographic pattern Microcalcifications 393 67%
  Solitary mass 129 22%
  Microcalcifications + mass 41 7%
  Negative 23 4%
Surgical management Quadrantectomy 434 74%
  Tumorectomy 88 15%
  Wide excision 64 11%
Axillary dissection Yes* 240 41%
  No 346 59%
Tumour pathological size ≤ 10 mm 222 38%
  11-29 mm 203 34.5%
  ≥ 30 mm 33 5.5%
  Unknown 128 22%
Histological subtypes Comedo 164 28%
  Cribriform 164 28%
  Papillary 94 16%
  Solid 64 11%
  Other 100 17%
Margin status Positive 4 1%
  Close 29 5%
  Negative 65 11%
  Unknown 488 83%
ER/PR status Positive 253 43%
  Negative 64 11%
  Unknown 269 46%
Radiotherapy technique 60 Cobalt Unit 311 53%
  Linear Accelerator 275 47%
Radiotherapy dose Median 50 Gy  
  Range 45 - 60 Gy  
Boost No 291 49.5%
  Direct electron field 234 40%
  Orthovoltage photons 58 10%
  Interstitial brachytherapy 3 0.5%
Boost dose Median 10 Gy  
  Range 8 - 20 Gy  
  1. * no nodal metastases were observed in any case.