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Table 2 Dosimetric characteristics at the 42 Gy and 40 Gy step

From: Higher toxicity with 42 Gy in 10 fractions as a total dose for 3D-conformal accelerated partial breast irradiation: results from a dose escalation phase II trial

Characteristic

42 Gy (n = 17)

40 Gy (n = 31 patients, 32 tumors)

 

Median

Min - max

Median

Min - max

PTV coverage

 

V100%

99

97 - 100

99

95 - 100

V95%

100

100 - 100

100

99 - 100

V90%

100

100 - 100

100

99 - 100

Ipsilateral breast

V32 Gy (%)

35

13 - 48

40

21 - 50

V24 Gy (%)

39

15 - 53

46

23 - 54

V16 Gy (%)

43

16 - 57

49

24 - 57

V8 Gy (%)

54

18 - 68

55

26 - 75

Non target breast

V40 Gy (%)

10

3 - 18

8

3 - 18

V32 Gy (%)

25

10 - 35

29

6 - 38

V20 Gy (%)

32

12 - 44

35

8 - 45

V10 Gy (%)

44

14 - 60

44

11 - 63

Ipsilateral lung

V20 Gy (%)

0

0 - 1

0

0 - 1

V10 Gy (%)

0

0 - 2

1

0 - 6

V5 Gy (%)

3

0 - 5

4

0 - 12

Heart

V20 Gy (%)

0

0 - 0

0

0 - 0

V10 Gy (%)

0

0 - 0

0

0 - 1

V5 Gy (%)

0

0 - 1

1

0 - 4

left breast cancer, n = 9

  

left breast cancer, n = 13