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Table 1 Patient and treatment characteristics

From: Risk factors of brain metastases in completely resected pathological stage IIIA-N2 non-small cell lung cancer

Characteristic

No.

%

Gender

  

Male

156

71.9

Female

61

28.1

Age

  

≤60

114

52.5

>60

103

47.5

Weight loss

  

≤5 %

208

95.9

>5 %

9

4.1

Smoking History

  

Negative

98

45.2

Positive

119

54.8

Preoperative KPS score

  

70

8

3.7

≥80

209

96.3

Preoperative hemoglobin

  

<120 g/l

18

8.3

≥120 g/l

199

91.7

Preoperative clinical stage N2

  

No

88

40.6

Yes

129

59.4

Histology

  

Squamous

87

40.1

Adenocarcinoma

112

51.6

Adenosquamous

12

5.5

Large cell

6

2.8

Tumor stage

  

T1

17

7.8

T2

163

75.1

T3

37

17.1

Laterality

  

Left

96

44.2

Right

121

55.8

Location

  

Upper/middle lobe

135

62.2

Lower lobe

82

37.8

Type of surgery

  

Lobectomy

196

90.3

Pneumonectomy

21

9.7

Histologic grade

  

Well/moderate

144

66.4

Poor

64

29.5

NS

9

4.1

Adjuvant chemotherapy

  

No

58

26.7

Yes

159

73.3

Postoperative radiotherapy

  

No

124

57.1

Yes

93

42.9

No. of dissected lymphonodes

  

1-20

103

47.5

20-60

114

52.5

No. of metastatic lymphonodes

  

≤5

112

51.6

>5

105

48.4

LNR

  

≥ 30 %

110

50.7

< 30 %

107

49.3

No. of metastatic mediastinal lymphonodes

  

< 3

107

49.3

≥ 3

110

50.7

No. of metastatic mediastinal lymphonodes station

  

1

136

62.7

2-4

81

37.3

Ratio of metastatic mediastinal lymphonodes station

  

≤50 %

108

49.8

>50 %

108

49.8

NS

1

0.5

  1. KPS indicates Karnofsky performance status; LNR, lymph node ratio; NS, not stated.