Table 1 Characteristics of patients with brainstem metastases
Characteristic | Value |
|---|---|
Patients (F/M), n | 36, (17/19) |
Lesions, n | 38 |
Median age (range), y | 62 (28-89) |
Primary Malignancy, n (%) | |
Lung | 14 (39%) |
Breast | 7 (19%) |
Colon | 4 (11%) |
Other | 11 (31%) |
Symptoms, n (%) | 25 (39%) |
Headache | 8 (22%) |
Weakness | 6 (17%) |
Ataxia | 7 (19%) |
Visual Changes | 6 (17%) |
Median KPS score (range) | 80 (60-90) |
Median GPA score (range) | 1.5 (0-3.5) |
RPA class, n (%) | |
I | 4 (11%) |
II | 30 (83%) |
III | 2 (6%) |
Number of intracranial metastases at time of SRS, n (%) | |
1 | 9 (24%) |
2 to 4 | 23 (61%) |
>4 | 6 (16%) |
Median interval between primary diagnosis and SRS (range), mo | 16 (1-190) |
Median tumor volume (cc), range | 0.94 (0.01-4.2) |
Location of treated brainstem metastasis, n (%) | |
Midbrain | 11 (29%) |
Pons | 25 (66%) |
Medulla | 2 (5%) |
WBRT for brain metastases before SRS, n (%) | 18 (47%) |
Median SRS dose (range), Gy | 17 (12-24) |
Treatment Fractions, n (%) | |
1 | 20 (56%) |
2 | 2 (6%) |
3 | 13 (36%) |
5 | 1 (3%) |
Treatment Modality, n (%) | |
Cyberknife | 34 (89%) |
Trilogy | 4 (11%) |