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Table 2 Comparison of dosimetric parameters for irradiation of bladder cancer and normal organs at risk (OARs) by using different treatment techniques.

From: Intensity modulated radiotherapy for elderly bladder cancer patients

   IMRT HT 2DRT P value
PTV UI 1.09 ± 0.01 1.01 ± 0.01 1.10 ± 0.03 IMRT vs. HT: p = 0.001
2DRT vs. IMRT: p = 0.19
2DRT vs. HT: p = 0.002
  CI 1.22 ± 0.06 1.20 ± 0.03 3.17 ± 1.01 IMRT vs. HT: p = 0.19
2DRT vs. IMRT: p < 0.001
2DRT vs. HT: p < 0.001
Right Femoral head (V30) mean
(%)
35.0 ± 0.2 6.0 ± 0.1 73.7 ± 19.7 IMRT vs. HT: p = 0.001
2DRT vs. IMRT: p < 0.001
2DRT vs. HT: p < 0.001
Left Femoral head (V30) mean
(%)
26.5 ± 0.3 6.1 ± 0.1 71.1 ± 22.9 IMRT vs. HT: p = 0.03
2DRT vs. IMRT: p < 0.001
2DRT vs. HT: p < 0.001
Rectum mean (Gy) 34.3 ± 9.1 25.4 ± 5.9 50.4 ± 8.1 IMRT vs. HT: p = 0.019
2DRT vs. IMRT: p < 0.001
2DRT vs. HT: p < 0.001
  V55Gy < 50%
(%)
4.7 ± 9.6 1.4 ± 2.8 46.1 ± 36.8 IMRT vs. HT: p = 0.28
2DRT vs. IMRT: p = 0.001
2DRT vs. HT: p < 0.001
Intestine mean (Gy) 29.2 ± 9.3 20.7 ± 6.6 40.2 ± 13.2 IMRT vs. HT: p = 0.034
2DRT vs. IMRT: p = 0.034
2DRT vs. HT: p < 0.001
  250 c.c.
< 45 Gy
(c.c.)
25.9 ± 30.1 10.8 ± 11.9 192.6 ± 132.6 IMRT vs. HT: p = 0.16
2DRT vs. IMRT: p = 0.001
2DRT vs. HT: p < 0.001
  1. The Vx is the percentage of femoral head volume that receives ≥ X Gy in the total femoral head volume.
  2. Abbreviations:
  3. 2DRT: Conventional whole pelvic radiation therapy; CI: Conformal index; IMRT = intensity-modulated radiation therapy; HT = helical tomotherapy; UI: Uniformity index.