Radiation Oncology

Table 2 Univariate and multivariate survival analysis

From: Stereotactic radiosurgery for brain metastases: analysis of outcome and risk of brain radionecrosis

Variable	No. of patients	Survival time Median months	univariate analysis P value	Multivariate analysis
				Hazard ratio (95% CI)	P value
Sex			0.1
Male	109	13.5
Female	97	14.7
Age (years)			0.1
< 65	122	14.6
≥ 65	84	13.3
KPS			<0.0001	2.2 (1.4-3.4)	0.007
≤ 70	95	10.1
>70	111	16.1
No of brain metastases			0.03	1.5 (1-2.2)	0.1
1	126	14.7
2-3	80	13.1
Primary tumor			0.2
Lung cancer	106	13.9
Breast cancer	38	18.2
Melanoma	34	12.7
Others	28	13.1
Extracranial disease			<0.0001	3.1 (1.8-5.0)	<0.001
stable	90	17.2
active	116	9.8
RPA Class			<0.0001
Class I	49	19.2
Class II	133	11.3
Class III	24	7.3

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ISSN: 1748-717X

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