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Table 2 Univariate and multivariate survival analysis

From: Stereotactic radiosurgery for brain metastases: analysis of outcome and risk of brain radionecrosis

Variable No. of patients Survival time Median months univariate analysis
P value
Multivariate analysis
     Hazard ratio (95% CI) P value
Sex    0.1   
Male 109 13.5    
Female 97 14.7    
Age (years)    0.1   
< 65 122 14.6    
≥ 65 84 13.3    
KPS    <0.0001 2.2 (1.4-3.4) 0.007
≤ 70 95 10.1    
>70 111 16.1    
No of brain metastases    0.03 1.5 (1-2.2) 0.1
1 126 14.7    
2-3 80 13.1    
Primary tumor    0.2   
Lung cancer 106 13.9    
Breast cancer 38 18.2    
Melanoma 34 12.7    
Others 28 13.1    
Extracranial disease    <0.0001 3.1 (1.8-5.0) <0.001
stable 90 17.2    
active 116 9.8    
RPA Class    <0.0001   
Class I 49 19.2    
Class II 133 11.3    
Class III 24 7.3