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Table 2 Comparisons of total length of copy number aberrations (CNA) by clinicopathological factor of breast cancers.

From: Significance of genomic instability in breast cancer in atomic bomb survivors: analysis of microarray-comparative genomic hybridization

Clinicopathological factor Total (N = 28)
n (%)
Mean total length of
CNA (bp)
P-value
Histological subtype    
Papillo-tubular 13 (46) 27,487,678 0.541)
Solid-tubular 3 (11) 41,158,092  
Scirrhous 12 (43) 61,520,542  
Histological grade    
I 4 (14) 49,011,523 0.322)
II 12 (43) 47,158,730  
III 12 (43) 32,711,871  
Axillary lymph node metastasis    
Positive 13 (62) 30,993,870 0.303)
Negative 8 (38) 59,602,019  
ER status    
Positive 14 (50) 53,249,555 0.433)
Negative 14 (50) 30,863,969  
HER2 amplification (FISH)    
Positive 9 (36) 28,970,829 0.753)
Negative 16 (64) 37,017,451  
C-MYC amplification (FISH)    
Positive 11 (48) 38,698,059 0.463)
Negative 12 (52) 22,102,472  
  1. 1): analysis of variance, 2): Jonckheere-Terpstra trend test, 3): t-test