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Table 2 Comparisons of total length of copy number aberrations (CNA) by clinicopathological factor of breast cancers.

From: Significance of genomic instability in breast cancer in atomic bomb survivors: analysis of microarray-comparative genomic hybridization

Clinicopathological factor

Total (N = 28)

n (%)

Mean total length of

CNA (bp)

P-value

Histological subtype

   

Papillo-tubular

13 (46)

27,487,678

0.541)

Solid-tubular

3 (11)

41,158,092

 

Scirrhous

12 (43)

61,520,542

 

Histological grade

   

I

4 (14)

49,011,523

0.322)

II

12 (43)

47,158,730

 

III

12 (43)

32,711,871

 

Axillary lymph node metastasis

   

Positive

13 (62)

30,993,870

0.303)

Negative

8 (38)

59,602,019

 

ER status

   

Positive

14 (50)

53,249,555

0.433)

Negative

14 (50)

30,863,969

 

HER2 amplification (FISH)

   

Positive

9 (36)

28,970,829

0.753)

Negative

16 (64)

37,017,451

 

C-MYC amplification (FISH)

   

Positive

11 (48)

38,698,059

0.463)

Negative

12 (52)

22,102,472

 
  1. 1): analysis of variance, 2): Jonckheere-Terpstra trend test, 3): t-test