Table 1 Characteristics of the analyzed cohort
Parameters | Patients |
|---|---|
N patients included | 112 (100%) |
definitive SIB-IMRT | 112 (100%) |
conc. syst Tx, IC, no syst Tx | 75 (70%), 24 (21%), 14 (12%) |
time interval | 3/2002 - 03/2011 |
male/female (%) | 96/16 (86/14) |
age, mean/median (range) | 62/61 years (33-87) |
WHO performance status 0/1/2 | 78 (70%)/33 (29%)/1 (1%) |
Diagnosis (%) | Â |
oropharynx | 62 (55%) |
hypopharynx | 22 (20%) |
oral cavity | 10 (9%) |
larynx | 5 (4%) |
others | 9 (8%) |
CUP | 4 (4%) |
T (number), % recurrence | 5, 4% (101 cc, 10-206) |
(mean volume, range) | Â |
CUP | 4, 4% (0 cc) |
T1 | 6, 5% (7 cc, 4-13) |
T2 | 15, 13% (34 cc, 5-63) |
T3 | 23, 20% (60 cc, 10-122) |
T4 | 59, 53% (77 cc, 12-206) |
N (number), % recurrence | 1, 1% (5 cc) |
(mean volume, range) | Â |
N0 | 10, 6% (0 cc) |
N1a-2b | 39, 13% (34 cc, 1-125) |
N2c | 37, 64% (30 cc, 1-119) |
N3 | 25, 23% (83 cc, 28-160) |
Gross Tumor Volumes (GTV) | Â |
mean primary GTV (range) | 62 cc (0-206) |
mean nodal GTV (range) | 41 cc (0-160) |
mean total GTV (range) | 104 cc (71-251) |
Follow up, mean/median (range) months | |
all patients | 26/21 (3-91) |
alive patients (n = 58) | 30/24 (5-85) |
dead patients (n = 39) | 18/13 (4-60) |