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Table 2 Treatment results

From: Whole-liver radiotherapy for end-stage colorectal cancer patients with massive liver metastases and advanced hepatic dysfunction

Patient No.

Dose (Gy)/fraction

Alkaline phosphatase (35 - 104 IU/L)*

Total bilirubin (0.2 - 1.2 mg/dL)*

Aspartate transaminase (0 - 40 IU/L)*

Alanine transaminase (0 - 40 IU/L)*

Post-RT chemo-therapy

Survival from RT (day)

1

21/7

N (306)

Y (6.5 → 2.2, 66%)

Y (118 → 69, 42%)

Y (43 → 27, 37%)

Y

123

2

21/7

Y (1246 → 350, 72%)

Y (3.0 → 1.6, 47%)

Y (114 → 29, 75%)

Y (43 → 7, 84%)

Y

94

3

21/7

N (554)

N (1.8)

Y (152 → 109, 28%)

Y (30 → 18, 40%)

N

64

4

21/7

Y (432 → 297, 31%)

Y (1.7 → 1.2, 29%)

Y (60 → 24, 60%)

Y (35 → 13, 63%)

N

22

5

21/7

Y (415 → 89, 79%)

Y (3.2 → 1.0, 69%)

Y (197 → 20, 90%)

Y (80 → 13, 84%)

Y

289

6

21/7

Y (675 → 366, 46%)

Y (15.8 → 4.2, 73%)

Y (101 → 33, 67%)

Y (49 → 23, 53%)

N

44

7

30/10

Y (1093 → 613, 44%)

Y (36.7 → 9.2, 75%)

Y (250 → 124, 50%)

Y (123 → 31, 75%)

Y

65

8

21/7

Y (615 → 376, 39%)

N (1.3)

Y (88 → 69, 22%)

Y (25 → 15, 40%)

N

34

9

21/7

Y (404 → 348, 14%)

N (7.0)

N (42)

Y (31 → 19, 39%)

N

44

10

21/7

Y (612 → 500, 18%)

N (8.4)

Y (142 → 107, 25%)

Y (76 → 30, 61%)

N

20

  1. *Normal range
  2. No improvement in liver function test. Level before RT in parentheses
  3. Improvement in liver function test. Levels before and after RT, and the reduction rate in parentheses