Table 6 ASTRO and GEC-ESTRO suitable patient recommendation selections for APBI outside of clinical trials
From: Accelerated Partial Breast Irradiation (APBI): A review of available techniques
| Â | Suitable group by ASTRO [138] | Low Risk group by GEC-ESTRO [137] |
|---|---|---|
Factors | Criterion | Criterion |
Age | > 60 y | > 50 |
BRCA 1, 2 Mutation | Not present | na |
Tumor Size | < 2 cm | < 3 cm |
T stage | T1 | T1-2 |
Margins | Negative by at least 2 mm | Negative by at least 2 mm |
Grade | any | any |
LVSI | Not allowed | Not allowed |
ER status | positive | any |
Multicentricity | unicentric | unicentric |
Multifocality | Unifocal with total size of < 2 cm | unifocal |
Histology | IDC, mucinous, tubular and colloid | IDC, mucinous, medullary, colloid |
DCIS | Not allowed | Not allowed |
EIC | Not allowed | Not allowed |
Associated LCIS | Allowed | Allowed |
Nodal status | pN0 (by SN Bx or ALND | pN0 (by SLNB or ALND) |
Neoadjuvant Therapy | Not allowed | Not allowed |