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Table 3 Accelerated partial breast irradiation clinical studies using external beam radiation

From: Accelerated Partial Breast Irradiation (APBI): A review of available techniques

Author No of cases Follow up (months) Fractionation scheme IBF Good/Excellent cosmesis
Vicini et al[104] 52 54 3.85 Gy × 10 (bid) 6% n/a
Vicini et al.[105] 91 24 3.85 Gy × 10 (bid) 0% 90%
Chen et al. [106] 94 51 3.85 Gy × 10 (bid) 1.1% 89%
Taghian et al.[107] 99 36 3.2 Gy × 4 (bid)$ 2% 97%
Formenti et al.[108] 10 36 (minimum) 5.0, 5.5, 6.0 Gy × 5 (10 days) 0% 100%
Formenti et al.[96] 47 18 6.0 Gy x5 (10 days) 0% n/a
Magee et al.[109] 353 96 (mean) 5.0 - 5.31 Gy × 8 (10 days)& 25% n/a
Leonard et al. [110] 55 34 median 3.85 cGy x10 (bid) 0% n/a
Hepel et al.[94] 60 15 3.85 Gy × 10 (bid) n/a 81.7%
Jagsi et al.[111] 34 > 24 3.85 Gy × 10 n/a 79.5%
  1. $Technique used were: mixed photons and electrons (63 patients), photons alone (16 patients), and protons (20), &Technique was electron field with a beam energy of 8-14 MeV, the majority being treated with 10 MeV, IBF = ipsilateral breast failure, n/a = data not available.