Neoadjuvant radiotherapy of primary irresectable unicentric Castleman's disease: a case report and review of the literature

Table 1 Summary of reports describing patients with CD treated with primary radiotherapy

Reference	Number of patients (n = 32)	Histopathology	Type	Dose	Response
Fitzpatrick et al. (1968)	1	-	Unicentric	4500	PR
	1	-	Unicentric	-	CR
Keller et al. (1972)	4	HV	Unicentric	1800-4300	PR
Emson et al. (1973)	1	-	-	3500	PR
Nordstrom et al. (1978)	1	PC	Unicentric	2700	PR
Nordstrom et al. (1978)	1	PC	Unicentric	2700	PR
	1	PC	Multicentric	1500	PR
Gaba et al. (1978)	1	HV	Multicentric	4500	NR
Weisenburger et al. (1979)	1	PC	Unicentric	2700	PR
Marti et al. (1983)	1	M	Multicentric	1200	CR
Stokes et al. (1985)	1	PC	Unicentric	3939	PR
Sethi et al (1990)	1	HV	Unicentric	4500	CR
Massey et al. (1991)	1	M	Unicentric	3040	PR
Latz et al. (1992)	1	HV	Unicentric	4000	CR
Veldhuis et al. (1996)	1	PC	Unicentric	4000	CR
Bowne et al. (1999)	1	HV	Unicentric	4500	NR
Chronowski et al.(2001)	4	HV	Unicentric	4000	CR
	4	HV	Unicentric	3960	CR
	2	HV	Unicentric	3960	PR
Neuhof and Debus (2006)	1	HV	Unicentric	4000-5000	NR
	1	HV	Unicentric	4000-5000	CR
Neuhof and Debus (2006)	1	M	Unicentric	4000-5000	NR
All Reports	32				CR: 14/32:43,8% PR: 14/32:43,8% NR: 4/32:12,4%

PC (plasma cell type); HV (hyaline vascular type); M (mixed HV and PC type); PR (partial response);
CR (complete response); NR (non response);

ISSN: 1748-717X