| Â | 2D | RTOG 0418-3DCRT | NEW-3DCRT | NEW-IMRT |
|---|
NEW-PTV
| 50% | 69% | 98% | 97% |
| Â | (p < 0.0009) | (p < 0.0009) | (p = NS) | Â |
Small Bowel
| 24% | 20% | 32% | 14% |
| Â | (p = 0.019) | (p < 0.0009) | (p < 0.0009) | Â |
Rectum
| 26% | 35% | 52% | 26% |
| Â | (p = NS) | (p = 0.002) | (p = 0.016) | Â |
Bladder
| 83% | 51% | 73% | 30% |
| Â | (p = NS) | (p = NS) | (p < 0.0009) | Â |
- Definitions: 2D -four fields with borders extending from the L5-S1 interspace to the bottom of the obturator foramen, and the front of the pubic symphysis to the S2-S3 interspace with standard blocking. RTOG 0418-3DCRT - the nodes at risk and upper 3 cm of vagina contoured as per RTOG 0418 guidelines, with 7 mm added to the vessels and 10 mm to the vagina to create the CTV. Four fields were used with the block edges 5 mm beyond the CTV to account for the penumbra. Superior extent of the CTV was 7 mm below L5-S1. Inferior extent of CTV was limited so that the CTV ended at the top of the femoral heads. NEW-3DCRT - Four field 3D plan with the CTV based on our newly defined nodal volumes. NEW-IMRT - Seven field IMRT plan with the CTV based our newly defined nodal volumes.
- All of the V45Gy reported were mean values from the 10 patients analyzed. P values reported were from comparison against the NEW-IMRT plan.
